Fluorobenzoic acid in the pharmaceutical industry
Posted at2020-09-29

Fluorine is the most electronegative atom. When organics are introduced into fluorine atoms or fluorine-containing groups, the strong electronegativity of fluorine atoms enhances the affinity between fluorine and carbon, which significantly changes the electrical effects of fluorine-containing organics And the simulation effect affects the acidity and basicity of the internal structure of the compound. When the fluorine atom replaces the hydrogen atom in the compound, the solubility of the lipid compound in the biofilm is enhanced, which promotes its absorption and transmission speed in the organism, and changes the physiological effect.


In recent decades, fluorine-containing drugs have developed rapidly, especially in small-molecule drugs, including sofibvir, which is used to cure hepatitis C, and favipiravir, which is used to treat new coronavirus. Fluorine-containing drugs play a very important role in the treatment of anti-tumor, anti-infection, central nervous, cardiovascular, immune and other diseases. Since 2010, on average, more than 30% of new chemical drugs approved by the FDA every year are fluorine-containing drugs, especially in recent years. The proportion of approved fluorine-containing drugs has exceeded 35%.
As shown below:


The use of organic fluorinated intermediates has grown to become a key component for many block-busters in the agrochemical and pharmaceutical Industry.
Fluorobenzoic acid is also playing an increasingly important role in pharmaceutical intermediates. Using our long-term knowledge, experience and capabilities in Fluorobenzoic acid, we provide you with excellent intermediatess based on efficient production processes.


Please see our recent hot-selling Fluorobenzoic acid series products are as follows:


Item

Name

CAS No.

1

3-Fluorobenzoic acid

455-38-9

2

4-fluorobenzoic acid

456-22-4

3

2,5-Difluorobenzoic acid

2991-28-8

4

2,6-Difluorobenzoic acid

385-00-2

5

3,4-Difluorobenzoic acid

455-86-7

6

2,3,4-Trifluorobenzoic acid

61079-72-9

7

2,4,5-trifluorobenzoic acid

446-17-3

8

2,4,6-trifluorobenzoic acid

28314-80-9

9

3,4,5-Trifluorobenzoic acid

121602-93-5

10

2,3,4,5-tetrafluorobenzoic acid

1201-31-6

                        Most of them are with high quality-99%+!

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