Apixaban is used to prevent harmful clots occurring in your blood. The usual dose is one tablet taken twice a day, morning and evening. The most common side-effects are bleeding (such as nosebleeds) and feeling sick.

About apixaban

Type of medicine	Anticoagulant
Used for	To prevent harmful blood clots following hip or knee surgery, or in people with atrial fibrillation (an irregular fast heartbeat)
Also called	Eliquis®
Available as	Tablets

Apixaban works by preventing your blood from clotting as quickly or as effectively as normal. It does this by blocking a substance in your blood which is involved in the development of blood clots, called factor Xa.

Sometimes harmful blood clots (called thrombi) can form in the veins of your legs, lungs, brain or heart, and cause a blockage. This is more likely to happen if you are having certain types of surgery, or if you have a fast irregular heartbeat. For many years, a medicine called warfarin has been commonly used to help protect against this. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Apixaban works in a slightly different way to warfarin, so people who take apixaban do not need to have regular blood tests.

You may be prescribed apixaban if you are having hip or knee surgery, or if you have a certain type of irregular fast heartbeat known as atrial fibrillation.

Before taking apixaban

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking apixaban it is important that your doctor knows:

• If You Are Pregnant Or Breast-Feeding.
• If You Have Had Any Surgery Recently (Other Than Hip Or Knee Surgery).
• If You Have An Ulcer In Your Stomach Or Intestines, Or If You Have Recently Recovered From One.
• If You Have High Blood Pressure.
• If You Have Any Medical Problems That May Increase Your Risk Of Bleeding.
• If You Have Any Problems With Your Liver Or Kidneys.
• If You Are Taking Or Using Any Other Medicines. This Includes Any Medicines You Are Taking Which Are Available To Buy Without A Prescription, Such As Herbal And Complementary Medicines.
• If You Have Ever Had An Allergic Reaction To A Medicine.

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Speranza Chemical Co.,Ltd. A leading supplier and manufacturer of Apixaban Intermediate, 5-Chlorovaleryl chloride，CAS No., 1575-61-7